个人简介

刘超副教授2019年2月起任职xk星空，博士生导师。主要研究方向包括：骨骼干细胞力学生物学，骨组织工程及再生，功能性骨骼植入器械。在JBMR, Bone, Journal of Biomechanics的学术论文总引用次数1000余次。多次获得国际骨科和骨骼组织研究协会青年研究者奖。最近在2019年国际生物科学及医学工程大会（ICBME）获得青年研究者奖。在入职xk星空一年内成功申请并主持深圳市基础研究面上项目、广东省高校青年创新人才项目。教学方面，承担了《生物医学工程（一）》、《骨骼组织工程》等本科生/研究生课程。

课题组主页：

教育背景
2010年-2016年 加拿大多伦多大学生物材料与生物医学工程研究所 博士
2008年-2010年 加拿大多伦多大学机械工程系 硕士
2003年-2008年 加拿大多伦多大学工程科学-生物医学工程 本科

工作经历

2024.11-至今 xk星空生物医学工程系 副教授，博士生导师

2019年-2024.11 xk星空生物医学工程系 助理教授，博士生导师

2016年-2019年 纽约大学生物医学工程系，Langone医学中心肌肉骨骼研究所 博士后

荣誉及奖励

2019年，国际生物医学工程会议年轻学者奖

2017年，国际肌肉骨骼研究协会联合会Travel Grant

2016年，美国骨与矿物研究学会青年研究员Travel Grant

2010-2014年，加拿大卫生研究院Travel Grant

2011-2013年，安大略省研究生奖学金

2008，2010年，芭芭拉和弗兰克米利根研究生奖学金

代表论文

1. Zhang, Jianing, Yanrong Tong, Yang xk星空, Minmin Lin, Yao Xiao, and Chao xk星空. "Mechanical loading attenuated negative effects of nucleotide analogue reverse-transcriptase inhibitor TDF on bone repair via Wnt/β-catenin pathway." Bone (2022): 116449.

2. Wang, Ziyan, Yang xk星空, Jianing Zhang, Minmin Lin, Chufan Xiao, Haoying Bai, and Chao xk星空. "Mechanical loading alleviated the inhibition of β2‐adrenergic receptor agonist terbutaline on bone regeneration." The FASEB Journal 35, no. 12 (2021): e22033.

3. Chao xk星空, Pamela Cabahug‐Zuckerman, Christopher Stubbs, Martin Pendola, Cinyee Cai, Kenneth A. Mann, and Alesha B. Castillo. "Mechanical loading promotes the expansion of primitive osteoprogenitors and organizes matrix and vascular morphology in long bone defects." Journal of Bone and Mineral Research (2019). 34 (5), 896-910

4. Chao xk星空 and Alesha B. Castillo. "Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair." JAAOS-Journal of the American Academy of Orthopaedic Surgeons 26.7 (2018): e153-e155.

5. Ma, Yu-Heng Vivian; Lam, Candy; Dalmia, Shreyash ; Gao, Peter; Young, Jacob; Middleton, Kevin; xk星空, Chao; You, Lidan. “Mechanical regulation of breast cancer bone metastasis via direct and indirect osteocyte signalling in vitro” Journal of Cellular Biochemistry. 2018, 119 (7), 5665-5675

6. Chao xk星空, Robert Carrera, Vittoria Flamini, Lena Kenny, Pamela Cabahug-Zuckerman, Benson George, Daniel Hunter, Bo xk星空, Gurpreet Singh, Philipp Leucht, Kenneth A Mann, Jill A Helms, Alesha B Castillo, “Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing” Bone. 2018, 108, pp. 145-155.

7. Qian, Weiyi; Gong, Lanqi; Cui, Xin; Zhang, Zijing; Bajpai, Apratim; xk星空, Chao; Castillo, Alesha; Teo, Jeremy; Chen, Weiqiang “Nanotopographic regulation of human mesenchymal stem cell osteogenesis” ACS Applied Materials & Interfaces. 2017, 9 (48), pp 41794–41806

8. Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, xk星空 C, Kennedy OD, Castillo AB, Egol KA, Leucht P. “The selective serotonin re-uptake inhibitor fluoxetine directly inhibits osteoblast differentiation and mineralization during fracture healing in mice.” Journal of Bone and Mineral Research. 32(4) 2017: 821–833

9. Chao xk星空, Xin Cui, Thomas Michael Ackermann, Vittoria Flamini, Weiqiang Chen, Alesha Castillo “Osteoblast-Derived Paracrine Factors Regulate Angiogenesis in Response to Mechanical Stimulation” Integrative Biology 8(7) 2016, 785-794

10. Chao xk星空, Xiaoqing Zhang, Michael Wu, Lidan You “Mechanical Regulation of Osteocyte Responses to Physical Damage in vitro” Journal of Biomechanics 2015. 48(16): 4221-4228

11. Ashutosh Parajuli*, Chao xk星空*, Wen Li*, Xiaoyu Gu, Xiaohan Lai, Christopher Price, Lidan You, X. Lucas Lu, Liyun Wang “Bone's Responses to Mechanical Loading are Impaired in Type 1 Diabetes” Bone 81 (2015) 152–160. (*Equal contributions)

12. Jia-Ning Zhang, Yan Zhao, Chao xk星空, Elizabeth S. Han, Xue Yu, Darcy Lidington, Steffen-Sebastian Bolz, Lidan You “The Role of the Sphingosine-1-Phosphate Signaling Pathway in Osteocyte Mechanotransduction Bone” Bone 79 (2015) 71-78.

13. Chao Wei, Beiyuan Fan, Deyong Chen, Chao xk星空, Yuanchen Wei, Bo Huo, Lidan You, Junbo Wang and Jian Chen “Osteocyte Culture in Microfluidic Devices” Biomicrofluidics. 9, 014109 (2015)

14. Wing-Yee Cheung, Chao xk星空, Craig A. Simmons, Lidan You, “Osteocyte Apoptosis is Mechanically Regulated and Induces Angiogenesis In Vitro”, Journal of Orthopedic Research, 2011 April ;29(4):523-30

15. Chao xk星空, Yan Zhao, Wing-Yee Cheung, Ronak Gandhi, Liyun Wang, Lidan You “Effects of cyclic hydraulic pressure on osteocytes” Bone. 46 (5), May 2010, pp. 1449-1456

16. Chao xk星空, Alesha B. Castillo, “Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair” Journal of the American Academy of Orthopaedic Surgeons. 2018 (invited review)

17. Jan-Hung Chen*, Chao xk星空*, Lidan You, Craig A. Simmons, “Boning up on Wolff’s Law: Mechanical regulation of the cells that make and maintain bone” Journal of Biomechanics 43 (1), pp. 108-118 (*Equal contributions)