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XU Chen
Associate Professor
0755-88018375
xuc@xingkong星空集团官网edu.cn

Dr. Xu Chen,Associate Professor , Department of Chemistry, Southern University of Science and Technology (Ph.D., leader of the independent research group), Shenzhen Overseas High-level “Peacock Project” talent (Class B). xingkong星空集团官网 2006, he graduated from the School of Chemistry and Chemical Engineering of Sun Yat-Sen University. xingkong星空集团官网 2011, he obtained his Ph.D. xingkong星空集团官网 organic chemistry from Peking University. From August 2012 to October 2016, Professor Sarah Reisman of the California Institute of Technology was engaged xingkong星空集团官网 the first post-doctoral research, completing the asymmetry of three complex star natural products Ryanodol, Ryanodine and 20-Deoxyspiganthine xingkong星空集团官网 15-18 steps. Synthetic and published xingkong星空集团官网 Science (Side by) and ACS Central Sceicne (independent); the work was reported xingkong星空集团官网 a number of very influential magazines such as C&EN, Forbes, and Science. xingkong星空集团官网 2017, Professor Robert Grubbs, a 2005 Nobel Laureate xingkong星空集团官网 Chemistry at the California Institute of Technology, conducted a second post-doctoral study on the design and synthesis of olefin metathesis metal ruthenium carbene complexes with high trans selectivity. xingkong星空集团官网 November 2017, he joined the Department of Chemistry of Southern University of Science and Technology to carry out independent research. The current research directions are: 1) efficient and concise total synthesis strategy for complex natural products with outstanding biological activity; 2) development of asymmetric agglomeration of metal organic catalysis And the method of bonding; 3) developing a late transition metal complex with a novel framework structure and exploring its photoelectric properties.

 

Representative Publications

  1. Chuang, K. V. (共同一作); Xu, C. (共同一作); Reisman, S. E.* A 15-Step Synthesis of (+)-Ryanodol. Science2016, 353, 912. This publication was highlighted xingkong星空集团官网 both C&EN: “Rapid Route to Ryanodol” andForbes(福布斯): “A Simple Way to Make a Complicated Molecule”.

  2. Xu, C.; Han, A.; Virgil, S. C.; Reisman, S. E.* Chemical Synthesis of (+)-Ryanodine and (+)-20-Deoxyspiganthine. ACS Cent. Sci. 2017, 3, 278.

  3. Xu, C.;Wang, L.; Hao, X. J.*; Wang, D. Z.* Tackling Reactivity and Selectivity within a Strained Architecture: Construction of the [6-6-5-7] Tetracyclic Core of Calyciphylline Alkaloids. J. Org. Chem. 2012,770, 6307.

  4. Xu, C.; Liu, Z; Wang, H. F.; Zhang, B; Xiang, Z; Hao, X. J.*; Wang, D. Z.* Rapid Construction of [5-6-7] Tricyclic Ring Skeleton of Calyciphylline Alkaloid Daphnilongeranin B. Org. Lett. 2011, 13, 1812.

  5. Wang, L.;Xu, C.; Chen, L.; Hao, X. J.*; Wang, D. Z.* Asymmetric Synthesis of the Tricyclic Core of Calyciphylline A-Type Alkaloids via Intramolecular [3+2] Cycloaddition. Org. Lett. 2014, 16, 1076.